Tag Archives: aderans research

Update on Aderans on Hair Cloning Technology

Aderans Research Institute (ARI) is currently in the middle of Phase II trials of its much-anticipated, much-delayed new cellular hair regeneration technology. The company hopes to “encourage” follicular cells to reproduce themselves via a method ARI calls the Ji Gami™ process, resulting in a virtually unlimited number of hair-generating cellular units produced. During this process, a small piece of tissue is removed from the neckline. Cells are cultivated in controlled conditions where they are encouraged to multiply by the addition of proprietary growth media. When enough new cells are formed, they are returned to the scalp, where they are injected and elicit new hair growth and thickness, ultimately producing more hair than the client had before. Candidates for hair regeneration may no longer be limited by the number of hairs on their head. ARI envisions a time when crowns (vertex) can be covered with full, natural hair regardless of the degree of hair loss.

The cell multiplication process, which involves a proprietary technology and “cooking” process, takes about 10 to 20 days. The cells are produced in ARI’s 8,000-square-foot laboratory facility in Atlanta, Georgia.

Conventional hair loss treatments, including hair transplants, run into a common problem: The limited amount of hair on a person’s head limits the degree of “redistribution” possible with transplants. For men with severe male pattern baldness especially, there is often an insufficient amount of hair remaining on the back of the head to provide a cosmetically satisfying result.

ARI’s new hair cloning technology could solve this problem… if it works. Several attempts have been made to create a viable hair cloning technology but the results, so far, have been limited. A common problem is that the hair that results tends to be very fine which also does not provide a cosmetically pleasing result.

ARI’s Phase II trial, which began in late 2008 and concludes in 2012, monitors patients for a full year after they have been injected with the regenerated cells. More than half the study participants so far have shown “significant” hair growth one year after administration, the company says.

“Interim data from the early stage of Phase II shows that about 50 to 70 percent of trial subjects are responding at a level that’s at least as good as anything that’s out there for growing hair, and we expect the later stage to get even better,” CEO Ken Washenik, Ph.D., said.

ARI treatments are entirely autologous. That means that ARI only attempts to generate hair growth using the participant’s own hair cells. No foreign growth media, such as plant- or animal-derived growth factors, are involved. When the cultivated follicles are restored to the participant’s scalp, he or she is receiving only his or her hair cells. This serum-free process delivers a degree of safety from complications unique to the field, the company says.

So far, Aderans has invested an estimated $100 million in its follicle cell multiplication technology and expects to spend an additional $50 million. The company is owned by the Japanese conglomerate Aderans Co., Ltd., the world’s largest manufacturers of wigs, which also owns the hair transplant giant Bosley.

To see more on ARI’s hair cloning technology, watch the update on the company’s hair multiplication technology presented by Dr. Ken Washenik during the 4th International Congress Research Against Hair Loss.

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Aderans Research and the Most Innovative Treatment for Baldness Available Now

Aderans Research is pioneering what could end up being the most innovative treatment for baldness to come along in a century. Unlike most other companies researching male hair loss and women thinning hair, Aderans is concentrating on a technology that uses a patient’s own cells (known as autologous cells) to develop a virtually limitless amount of new hair follicles. This will obviously be a very expensive treatment for baldness because it will be, in a sense, customized for each patient.

Aderans calls the technology it is developing the Ji Gami™ process. Here’s how it works. Technicians remove a small piece of hair follicle tissue from a patient’s scalp, generally near the neckline. The hair follicle cells are then cultured in a laboratory so that they multiply. When a sufficient amount of new cells have been grown, the hair follicle cells — each unique to the individual patient — are then injected into the bald or thinning areas of the patient’s scalp.

Aderans executives believe they are on the verge of a true cure for baldness, a treatment for hair that will result in almost unlimited new hair growth. This approach is not the same as those attempting to use growth factor serums to regenerate existing dormant hair follicles. Instead, Aderans is attempting to grow new follicle cells, made from cells taken from the patient’s own scalp, and inject them into balding areas for hair growth.

How is the research proceeding? At the moment, Aderans is completing its Phase II clinical testing of its hair fall remedies. A total of more than 350 hair loss sufferers are now enrolled in the clinical trial from cities across the country. At the 2012 Winter Clinical Dermatology Conference in Maui in January, Aderans CEO Dr. Ken Washenik (M.D. & Ph.D.) presented a paper on “Emerging Therapies for Hair Loss” that received a standing ovation from the assembled dermatologists and hair restoration doctors. That’s because Dr. Washenik reported that the Clinical Trials of the Ji Gami™ process are going very well. While the process is not a magic pill that provides install hair like a Chia Pet, it does appear to grow new hair where none existed before — and, what’s more, can provide a virtually limitless supply of donor hair follicles for hair restoration doctors to use. In earlier tests, released in 2010, Aderans reported that more than half of participants in its clinical study showed “significant hair growth” one year after the cell product treatment was administered.

If you’d like to read more technical information about the early developments of this technology, then click on the link below for a PDF…

Bioengineering the Hair Follicle: Fringe Benefits of Stem Cell Technology

The Aderans “cell engineering” approach appears to be the most promising treatment for baldness on the horizon at the moment, according to the company’s spokesman, Vern Liebmann. That’s because the cell engineering approach offers hope for bald men who do not have enough donor hair for a cosmetically satisfying traditional hair transplant. With a limitless amount of donor hair follicles, the Aderans hair treatment could cover virtually any scalp with thick, natural hair.

If you’d like more information about Aderans and its clinical trials, fill in the form below:

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