Grow Hair Faster with Growth Factor Serums, Anti-DHT Hair Growth Products

If you want to grow hair faster, you should consider trying some of the new hair growth factor serums and anti-DHT products that have come along in recent years. While not a panacea and certainly not a “cure” for hair loss, these new hair growth products do grow hair faster than many things tried in the past.

Grow Hair

To grow hair faster, you need to focus on the root causes of hair loss and hair thinning. For years, researchers have theorized that hair loss is caused by a genetic hyper-sensitivity to the hormone dihydrotestosterone (DHT), a derivative from the male sex hormone testosterone. The theory has been that hair follicles gradually shrink and then die when exposed to large amounts of DHT. As a result, the theory goes, to grow hair faster you simply have to limit the amount of DHT on the scalp. There are a number of highly effective anti-DHT shampoos and conditioners on the market now. For example, DS Laboratories Revita Shampoo and Revita.COR conditioner are popular with women who want to grow hair faster and with men who want to regrow lost hair.

The most exciting development in recent years to grow hair, however, has been the discovery that DHT does not cause hair follicles to die, a previously thought, but only to go asleep. In a sense, therefore, hair follicles hibernate. Scientists have discovered a number of special proteins, known as growth factors, that are like chemical alarm clocks and wake dormant hair follicles back up. These growth factors have been proven to stimulate new hair growth and to grow hair faster. One of the earliest and most popular of these new growth factor serums, made from adult stem cells, is Cygenx’s RegenRXx Growth Factor Serum 90. By flooding hair follicles with these specialized chemical wake-up messages, growth factor serums stimulate the follicles to grow hair — to grow hair faster than normal and to regrow hair where none was growing before.

Grow Hair Faster

The problem now is scalp penetration. One solution, which the San Diego company Histogen is working on, is to develop a surgical procedure to inject growth factors beneath the skin and more directly into the scalp. The problem with this approach is that it requires FDA approval, will be expensive and is not available right now.

Another solution is the use of a dermal roller. A dermal roller, which Cygenx sells along with its RegenRXx Growth Factor Serum, puts hundreds of micro holes in your scalp and has been proven to help grow hair faster all by itself. Many hair growth physicians advocate the use of the dermal roller alone to grow hair. However, there is always the possibility of infection and many experts caution that, if you do use a dermal roller, you should do so under the supervision of a doctor — just to make sure you don’t accidentally get an infection.

The third thing you can do to grow hair faster is to try cold laser treatments, such as the LaserComb. The FDA has approved the use of cold lasers as a legitimate hair treatment to grow hair and to grow hair faster. Some people are satisfied with the results and find that, at the very least, the cold lasers slow hair loss. Others are disappointed.

The bottom line is this: If you would like to grow hair, there are more options today than in the past. If you just suffer from thinning hair or would like thicker hair or to grow hair faster, then these hair loss products might actually help — anti-DHT shampoos and conditions like Revita Shampoo and Revita.COR, growth factors serums like RegenRXx, and cold lasers like the LaserComb. If you suffer from severe male pattern baldness, however, then these hair growth products likely will leave you disappointed. They will help you grow hair and even grow hair faster, but won’t give you the volume you need for cosmetic purposes.

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Is Your Hair Falling Out from Stress?

There are indications that hair falling out from stress and malnutrition are associated. The suggested rationale for the link between the two is that one creates the other. It doesn’t matter which come first. Each exacerbates the other condition. As a result, the treatment method chosen must address both issues simultaneously.

Stress related hair loss can occur after surgery or a severe illness. It is also associated with the stress of combat or living in a war zone. Others sources of stress include work-level overload and abusive relationships. The human body is a fragile eco-system teetering on the balance of the way in which you live. Hair falling out from stress can be treated using a combination of methods.

The severity of shedding and it’s permanency must first be determined before treatment begins. In some instances, hair falling out from stress is only temporary and will grow back on its own. In either case, the issues of poor nutrition needs to be handled as soon as possible. There are many unique ways to acquire the minerals and nutrients needed. One such way is by using a wider variety of herbs in cooking.

For permanent manifestations of hair falling out from stress, counseling is usually one of the treatments used. Sometimes, such counseling is minimal just to help you deal with the fear associated with the trauma experienced – such as a death in the family. Longer-term emotional counseling is used for those who have disorders such as posttraumatic stress syndrome. In either case, hair loss can be stopped by combining topical treatments.

Another situation where hair falling out from stress occurs is when you live with an abusive situation. This can mean emotional or mental abuse as well as physical confrontation. Often people who live in abusive situations do not realize that this is the case. Abuse happens slowly over a period of time and people adjust to it. One reaction is to attempt to be perfect and not disappoint the other party.

Hair falling out from stress in children nearly always requires some form of emotional counseling. Frequently, the abusive situation is discovered with children who habitually pull, tug or twist their hair to the point that it falls out. Abusive situations are not the only reason for children twisting and pulling their hair, however. Other reasons causing the stress may be the cause.

No amount of nutrition or treatment can change the reason for your stress. But, hair falling out from stress is a serious symptom that there is something medically wrong and deserves your attention to fix it.

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My Hair is Falling Out: Why is My Hair Falling Out?

When I started to see that my hair is falling out, I naturally sought out hair loss treatments that other people have found useful. Here is what I found out.

Androgenetic alopecia (male and female pattern balding) is by far the most common cause of hair loss amongst men and a serious problem for many women. There are three important components which are responsible for both female and male balding:

1. A genetic predisposition for balding to occur.

2. Excessive presence of male hormones.

3. Aging – enough time for the first two factors to occur.

Both men and women produce male hormones that have a useful role to play in both sexes; but the fact that androgens occur in much higher concentrations in men explains why male pattern baldness is more common than the female balding.

What is making my hair fall out? It is metabolism of male hormones (androgen/testosterone) which is main cause of hair loss and male and female pattern balding both in men and women.

The metabolism of androgen involves an enzyme called 5 alpha reductase which combines with the hormone (testosterone) and converts it to DHT (Dihydro-testosterone). DHT is a natural metabolite of our body.

Why is my hair falling out? Some individuals, both men and women, are genetically pre-disposed to produce more DHT than the normal individuals. It is this accumulation of DHT and its effect on the cells inside the hair follicle and root which is one of the primary causes of male and female pattern balding.

When DHT gets into the hair follicle and root, especially a region called the dermal papilla, it changes the cell’ activity and prevents necessary proteins, vitamins and minerals from providing nourishment needed to sustain life in the hairs of those follicles. Consequently, hair follicles are reproduced at a much slower rate. This shortens their growing stage (anagen phase) and or lengthens their resting stage (telogen phase) of the follicle. DHT also causes hair follicle to shrink and get progressively smaller and finer. This process is known as miniaturization and causes the hair to ultimately fall. DHT induced androgenetic aloepcia is responsible for 95% of all hair loss.

Blocking the synthesis of DHT at the molecular level forms the basis for the treatment of MPHL (male pattern hair loss) and FPHL (female pattern hair loss). There are many natural DHT blockers and a number of drugs which are used for medical hair restoration.

There has been a great deal of progress in the field of hair replacement and restoration in the past few years. Surgical techniques have improved greatly from the days when hair replacement first began. All hair replacement techniques involve the use of your own hair; therefore, hair replacement candidates must have some healthy hair, usually at the back and sides of the head. The process is a relatively safe procedure when performed by a qualified surgeon, however as with any surgery there are risks. Candidates must be checked for uncontrolled high blood pressure, blood-clotting problems, or skin that scars excessively, as these conditions may make healing difficult. Small pieces of hair growing scalp grafts are removed from areas of the scalp with healthy hair and are placed where hair is thinning. There are three major types of grafts: punch grafts, mini-grafts, and micro-grafts. Punch grafting takes about 10-15 hairs and places them in the scalp. This was the first type of technique to be developed, and when first developed caused a patchy look in many candidates. The technique has been improved since the first days of being developed, and the new mini-graft technique has also been added as an option. Mini-grafts contain only 2-4 hairs per graft, and therefore look much more natural. Micro-grafts are still smaller grafts that contain one to two hairs each. To maintain healthy circulation of the scalp, grafts are placed 1/8th of an inch apart. Local anesthesia is usually sufficient for these procedures, and several procedures are usually required to achieve the desired result. Post-surgery, a period of approximately 10 days of no sexual or strenuous activity is recommended, as strenuous activity may cause bleeding from the graft areas.

Of course surgery is a serious option, and often an expensive one as well. For those not wishing to undergo surgery for either reason, the option of non-surgical hair additions is often explored. Many professionals have developed techniques to add hair to existing hair on your scalp that look very natural. Weaves, fusions, bonding, cabling and micro linking are some of the techniques used to bond hair to the existing hair or scalp non-surgically.

Many jokes were made in the past about wigs and toupees, and they have gained an unfavorable light amongst many people because they were so obvious on the wearer. Today’s toupees and wigs are often made of real hair and are very well styled, causing them to look ore natural on the wearer. These hairpieces are held in place by affixing adhesive to the scalp and stay in place through vigorous exercise. Of course you will need to seek a professionally made toupee in order to make it worth your while, and you should purchase at least two so that you can maintain them properly, servicing one while wearing the other. A professionally styled and fitted toupee is expected to cost upward of $600 to $1000 in today’s market. Of course no one wants to go through the embarrassment of wearing the obvious “rug” on top of your head, so if you are not willing to spend the money it takes to purchase a professional toupee then it is probably best to not wear any hairpiece at all.

Structured hairpieces as they are called are a semi-surgical approach that permanently attaches hair to the scalp by stitching the hair to the bald scalp. This procedure is not recommended, as it is a process that involves introducing a foreign material to the scalp. Most ethical surgeons do not perform this procedure any longer as they are generally deemed to be ethically inappropriate. If this procedure is recommended to you, get a second opinion from a trusted physician.

A much safer procedure is hair weaving, yet this can only be used if hair is thinning and large balding areas are not present. The process is also called hair intensification or hair integration. Strands of synthetic or real hair are braided or weaved into your own existing hair giving an appearance of a full head of hair. This procedure does have its drawbacks, because it can make the scalp difficult to access, interfering with proper hair and scalp maintenance necessary for the health of your remaining natural hair, and this method can also stress existing hair since the artificial hair introduced through weaving is attached to it. This method is usually expensive, costing several thousand dollars per application, and being that because of the aforementioned drawbacks it can only be left in for a few weeks at a time it is usually impractical for the average person.

It is highly recommended that one seek professional assistance with these procedures from licensed beauticians or barbers, and have a patch test done to the skin if using adhesives to test for skin sensitivities. Extra care must be taken to maintain cleanliness of the hair and scalp when wearing added hair in order to maintain the health of existing hair and the scalp in general. Of course, if you are undergoing chemotherapy or are in the early stages of diagnosed alopecia areata then these procedures should be avoided as the hair they are connected to is likely to fall out as well. Either waiting for a period of time or obtaining a full prosthesis is recommended in these cases.

Yet still there is another type of treatment which is a spray of micro fibers made up of the same substance that hair is made of: keratin. If your hair is simply thinning, while you are investigating a more permanent solution to your hair loss problems or in the process of employing a particular process that takes some time, you can use these substances to cosmetically produce the appearance of thicker and fuller hair. The substance is marketed under several different names, one such being Topik®. Being a temporary solution it is relatively inexpensive, and can provide some immediate aesthetic results to bolster confidence and optimism as you work on more permanent solutions.

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Clinical Trials to Grow Hair – Call for Participants 2012

Merck Pharmaceuticals is calling for people living in the New York Area who would like to participate in the Hair Loss Gene Chip Study. The study is under the direction of Dr. Animesh Singha. The project will use micro-arrays or gene chip technology to understand the complex processes need to grow hair. This is a study using RNA rather than DNA genetic models.

Even though researchers are focusing efforts for participants who live in the New York area, they are hoping to find a method where remote sampling can be done for the Phase I project. Merck’s participation in the study to grow hair involves gaining a better understanding of how their product, Propecia, works in different diseases. These trials are for men only between the ages of 18 and 41 in healthy condition.

Aderans is conducting clinical trials and there are still opening in some clinics in the U.S. This is a phase II study as they prepare to get one of their products approved by the FDA and into the pipeline for production. These studies are for males only and involve an in-depth research project to grow hair with men who have androgenetic alopecia.

A collaborative effort between Europe, Asia and U.S. doctors and sponsored by Kerotene, a European product, is doing open trials in 2012 and accepting applicants for several different studies now. The projects involve transplant methods and success rates using their new procedures.

They are seeking identical twins with mild to moderate balding in each of various studies for replacement therapy to grow hair. Both males and female twins are encouraged to participate. The company and sponsors will pay for the transplant procedure but the participants must pay for their own transportation and accommodations during the procedure. The facilities in Zurich, Switzerland will be the location for the clinical trials.

Johnson & Johnson is considering open trials on hair loss restoration by the end of 2012. They have yet to release the precise information on the manner or methods that will be used in these trials.

If you have problems with hair loss or the inability to regrow hair, check out the various clinical trials that may interest you. Several other pharmaceutical teams are preparing to have open trials this year but have yet to find sponsorship. These are usually cutting edge studies that add to the progress of treatments available to grow hair.

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Can Stem Cells Alter Hair Follicles Growth?

The process of hair follicles growth is one that has only been understood on the cellular level in the last ten years. There were a number of theories when research began. However, as is normally true with all theories, surprises happen. Scientists accidentally stumbled across an unexpected result when investigating a compound to be used for intestinal relief in cases of stress. The compound grew hair instead.

The furry mice surprise discovery led to studies on the reaction of hair follicles growth in signaling paths. The knowledge of how communication receptors interact with genes was not yet documented. One of the findings led to replicating the stem cells from healthy hair follicles in compound that included the fatty tissue found beneath the skin.

This fatty tissue carries hair stem cells, as well. Some research labs are using the tissue cells to replicate hair follicles growth studies. Sometimes referred to as “fat” stem cells, these tissue replications indicate that hair cells are a much more complex biosystem than originally thought.

Hair follicles growth has been assumed to be cyclical but the cycle mechanism was only realized during research into replication projects. Scientists expected that the cycle of growth and rest in hair growth was between 6 months and a year. The studies showed that there are millions of follicles at rest while others are in some phase of growth. The cyclical activity actually takes between 5 and 7 years.

This lengthy rest period explained why hairs were not immediately replaced when some fell out. In closer studies, it became evident that each cell within a follicle has a particular purpose for existing. In laymen’s terms, all cells are specialists. There are communicators and receptors. When the pathway between them is blocked by an overproduction of hormones, for example, the cells that are to initiate growth activity remains dormant.
The other issue that is discovered to exist in male pattern baldness, female pattern baldness and hypotrichosis simplex is the miniaturization of follicles. Scientists state that this is caused in part by the increase of the hormone, DHT. DHT is thought to create a blockage in the production of follicles by shrinking them. The other discovery by scientists is that a gene called APCDD1 has a lot to do with this miniaturization.

From that discovery, pharmaceutical projects are in process to use stem cells from this gene, from healthy sheath caps, and from tissue around the follicles in developing a stem cell solution to repair and replace hair follicles growth that has been damaged.

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Powerful Cancer Drugs Offer Hope for Patients Suffering from Alopecia Universalis… and MAY Lead to Baldness Cure

A breakthrough new treatment for the rare form of baldness known as alopecia universalis — in which patients have no hair whatsoever on their entire bodies — may turn out to be useful for treating ordinary baldness and hair loss, although researchers are still not sure.

Using a drug designed to treat rheumatoid arthritis, a Connecticut dermatologist named Dr. Brett A. King helped a 25-year-old patient with zero hair on his body grow a full head of hair in eight months.

The man was afflicted with alopecia universalis, a rare form of hair loss that has no cure or long-term treatment.

The problem: The drugs are expensive… very, very expensive. According to one account, the drugs can cost up to $25,000 a year with insurance. What’s more, they are serious drugs with serious potential side effects. But all indications are, they work!

At the very least, this new treatment offers the first really hope for people who suffer from alopecia universalis. At least once a month, we get an email from patients, or parents of patients, who suffer from this type of hair loss and we have had little hope to offer them… until now.

There are several varieties of alopecia. The most common form is alopecia areata, which affects 4.5 million Americans. In this form of the disease, the hair falls out in patches. Alopecia universalis is the rarest form of the illness, and involves the loss of nearly all body hair.

It is an autoimmune disease in which the hair follicles are attacked by the body’s own immune system.

Though there’s a long way to go until King and his colleagues declare victory over baldness, he said his recent findings are promising. “It is really exciting,” Dr. King, an assistant professor of dermatology at Yale University School of Medicine, told a local newsletter. “At the very least, this means many folks who have been told there isn’t a solution may now have a solution.”

King enrolled his patient in a new clinical trial for the drug Xeljanz, designed to cope with the autoimmune disorder rheumatoid arthritis.

King hopes to convert Xeljanz into a cream that can be used topically to cure baldness in patients. With the transition from pill to cream, the drug will have minimal side effects on the body and attack the problem right at the source.

Doctors in New York have tried the new type treatment out on three other patients… and once again, have had great success.

Doctors designed a pilot trial after identifying which immune cells were responsible for destroying hair follicles in people with the condition. Within four or five months of being put on a different autoimmune drug, ruxolitinib, all three patients experienced complete hair regrowth.

Ruxolitinib, which is sold under the named Jakafi and Jakavi, is a drug used for the treatment of intermediate or high-risk myelofibrosis, a type of bone marrow cancer It is also being investigated as a treatment of other types of cancer as well as for psoriasis and alopecia areata. Jakafi, the brand name for ruxolitinib, costs $8,753 for a month’s supply, which amounts to more than $100,000 a year,

What’s more, there is no connection between alopecia and male pattern baldness! That raises an interesting question: If ruxolitinib and tofacitinib promote hair growth in people with alopecia, could they be used to treat run-of-the mill male-pattern baldness? No one knows… although researchers are investigating just that question now.

“We’ve only just begun testing the drug in patients, but if the drug continues to be successful and safe, it will have a dramatic positive impact on the lives of people with this disease,” said Dr Raphael Clynes, from Columbia University Medical Centre in New York.

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Have Hair You Can Be Proud of with Nioxin Hair Loss Products

Nioxin is a brand that has curved a niche when it comes to managing and arresting hair loss. Nioxin hair loss products are not new in the market and they have in fact been around for 26 years. Their hair care products have been praised for their wonderful effects in strengthening and making the hair dense. The Nioxin hair loss treatment promises to deliver denser looking hair and this is exactly what they deliver.

Have Hair You Can Be Proud of with Nioxin Hair Loss Products

Nioxin system hair loss treatment contains six treatments and each of them has their unique solutions. These are:

  • Nioxin System 1: This system is essential in treating thin looking hair. It is also very effective in preventing hair loss in fine textured hair and natural hair as well.
  • Nioxin System 2: The second system has noticeably thinning hair and it can also be used on natural hair as well.
  • Nioxin System 3: This treatment has been designed to treat thinning hair that has been chemically processed.
  • Nioxin System 4: The forth treatment has been developed to treat fine textured hair that has been chemically treated as well.
  • Nioxin System 5: This treatment is for normal and thin looking hair as well. The treatment can also be used on medium to coarse textured hair that is either natural or chemically treated.
  • Nioxin System 6: The final Nioxin system treatment is made for medium to coarse textured hair that is noticeably thinning. This treatment can also be used on hair that has been chemically treated.

One of the things that you will notice with these treatments is the fact that they have been designed to help treat thinning in all types of hair. People with coarse and fine textured hair are all accommodated. Both natural and chemically treated hair can be treated with these Nioxin hair care products.

How Can Nioxin Hair Loss Products Help Renew Your Scalp?

Nioxin has an interesting range of hair loss products which work to reduce breakage in particular. Hair breakage is mostly as a result of weakened hair and this is very common in over processed hair, as well as hair that is styled using the wrong techniques or styling products. The scalp renew dermabrasion treatment and density restoration treatment from Nioxin both promise to help restore the health of your scalp so as to give your hair a new lease of life. As you may have guessed with the term dermabrasion, this treatment helps to exfoliate the scalp by removing hair follicle build up. The treatment accelerates scalp regeneration by 34 percent and enables the hair to grow healthier and stronger as well. This is an anti-aging treatment that revitalizes the scalp by renewing it.

Nioxin hair loss products use a combination of ingredients which cleanse the scalp to create a healthy environment. They also have conditioning properties which moisten the hair and protect it from the harmful effects of the environment. These hair loss products have five effects on your hair. They:

  • Reduce hair breakage
  • Make the hair look denser
  • Amplify the texture of the hair
  • Strengthen the hair from cuticle damage
  • Cleanse excessive sebum

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Biostem Seeks to Expand Its Stem Cell Hair Loss Products Worldwide

Biostem Seeks to Expand Its Stem Cell Hair Loss Products Worldwide

Biostem U.S., which describes itself as a “technology licensing company” with hair regrowth treatment using using human stem cells, is seeking to expand its operations worldwide. The company, a NEvada corporation based in Clearwater, FLorida, recently announced the change of its stock symbol to HAIR. The company offers hair growth treatments that feature a combination of Platelet Rich Plasma (PRP) injections, the user of low level lasers, nutritional supplements and other hair products to stimulate new hair growth. The company is hoping to license its technology to private clinics around the world. Its first clinic outside of the Clearwater area is in Ohio.

Biostem was founded by two hair restoration doctors, Dr. John Satino and board-certified Medical Director Dr. Michael Markou, who work out of the Hair and Scalp Clinics in Clearwater, Florida.

It appears that the technique used by Dr. Satino and Dr. Markou is a variation on a technique used by some other hair restoration doctors around the world, which is to gently “wound” or irritate the scalp and then use injections of concentrated growth factors, taken from Platelet Rich Plasma, to stimulate hair follicle regeneration. Recent research has show that the “healing” process in skin seems to have this stimulating effect. Dr. Satino and Dr. Markou use special CO2 lasers to assist them in the gentle wounding of the scalp. They follow up the PRP process with other proven hair growth treatments, including low level lasers and nutritional supplements.

In addition to patients suffering from male pattern baldness, Dr. Satino and Markou have also used their techniques for patients suffering from alopecia areata and female hair loss.

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What You Should Know About Natural Hair Loss Products

If you were to search online for natural hair loss products, you would be surprised by the long list of websites that claim to provide remedies for hair loss. While it is understandable that many of us prefer to go the natural route when it comes to treatment, we also need to be very wary of the information we source from the internet. What many people should know is that most of these natural remedies do not work. This is because these remedies do not deal with the root cause of the problem. Needless to say, most of the remedies are founded on claims that have no sort of evidence. You need to understand that hair loss is caused by various factors. In some cases, it could be due to certain medications such as chemotherapy while in most cases it is a simple case of using harsh treatments on the hair or aging. A holistic view of the hair loss needs to be considered and you would be surprised to learn that with proper nutrition, hair loss may not even occur.

How to Identify Natural Hair Loss Products That Don’t Work

With so many natural hair products in the market, how can you weed out the fakes to identify only the effective treatments?

  • The first thing you need to do is have a look at what the product does. Hair loss products are not meant to hide the fact that you are losing hair with some camouflage of sorts. They are meant to reverse the thinning and balding by encouraging the actual growth of hair. If the hair product does not work to stimulate hair growth, it is not worth your time.
  • Look at the promises that come with the product. Hair does not grow overnight and a product that promises results in a few days is definitely a fake. It’s important that you realize that hair grows slowly yet naturally sheds quite a lot. It may therefore take you a few months before you can even begin to see slightest effects of the treatment. Hair re-growth will take a few years before you can see definite results.
  • You also need to analyze the ingredients very carefully. Make sure that the active or prime ingredients in the product are tested and approved by the FDA. This is information you can easily find online and thousands of ingredients have been tested to verify their effects in managing hair loss.

Which Natural Hair Loss Products Work?

Though not many, there are some hair loss products that actually work. Treating hair loss is all about stimulating growth and this means reducing the anagen phase. You need to look for ingredients that strengthen the hair and prevent breakage. Some of these natural ingredients include:


  • Aloe Vera
  • Saw palmetto
  • Jojoba oil
  • Castor seed
  • Avocado oil
  • Rosemary extract
  • Biotin


Of course these are just some of the most prominent ingredients used in natural hair loss products. It’s always recommended that you seek advice from a dermatologist before you begin using any natural products.

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Wound healing and hair cloning

Hair loss or Androgenetic alopecia (AGA) is characterized by the miniaturization of the hair follicles in susceptible individuals and occurs in a defined pattern on the scalp.

Hair loss in aging men and women is characterized by these “damaged hair follicles.” Normal hair growth depends on a cycle in which periodic regeneration of the underlying hair follicle occurs through a process directed by stem cells.

Within the follicle, normal stem cell function is essential for hair follicle regrowth. What has been discovered in just the past few years, through studies of wound healing in burn victims and other patients, is that it is possible to actually grow new hair follicles and, as a result, new hair. The formation of new follicles and hair growth was shown to be associated with a cascade of cellular and biochemical events during the wound healing process.

By studying wound healing at the cellular and molecular levels, the skin was observed to have the ability to revert to a more primitive or “embryonic” state as progenitor cells “migrate” to the wounded area, restoring the regenerative capacity of the skin not previously thought to occur in adults.

The regenerative response includes new hair follicle formation, allowing new hair to grow at the restored site.

A major part of the wound healing cascade is the release of growth factors and cytokines from stem cells into the layers of the scalp at the site of the wound. These growth factors and cytokines function like a light switch, turning on lost or decreased function of the hair follicle.

Although dihydrotestosterone (DHT) is only one factor, and a minor one, in causing the unhealthy minaturization of the follicle in male pattern baldness process, it has received much attention. Several products are now on the market that attempt to restore hair growth based on interacting with the DHT pathway. These DHT specific products have demonstrated limited efficacy in growing new hair yet can show debilitating side-effects, including sexual dysfunction.

Based on the similar etiologies of male pattern baldness through DHT, it was thought that naturally occurring growth factors may also benefit the treatment of hair loss through the DHT pathway, but without the side-effects seen with other products. More importantly, the direct effects of topically applied cytokines and growth factors to the hair follicle restores the normal physiology and anatomy of the hair follicle and is the critical factor in restoring hair growth.

Below is the first example of a placebo-controlled, double-blind study undertaken to examine the benefit of these naturally occurring growth factors in the treatment of hair loss.

Objectives: The goal of this study was to test naturally occurring growth factors in the treatment of AGA.

Subjects included in this study were males between the ages of 25 and 65 years of age, in good health, with mild to moderate AGA.

Results: The results of this study showed a highly positive response to treatment. The blinded investigative staff assessment report showed that over 90% of study subjects dosed with the active study formulation were rated as improved at the final visit. Patient self-assessment demonstrated that 94% of the patients saw significant improvement in hair growth and prevention of hair loss.

Conclusions: This study establishes the effectiveness of naturally occurring growth factors for the first time in the treatment of hair loss. Growth factor technology has been used to generate completely new hair follicles for the first time in normal adult males. The researchers were able to induce the regenerative response, including new hair follicle formation, by applying a combination of factors to the scalp. This work showed that the application of these growth factors resulted in skin triggered molecular pathways, allowing a new topical treatment option for re-growing hair.

Caution: the application of any artificially created or synthesized signaling molecule is discouraged for two reasons; they lack potency and they may cause unnecessary secondary side effects. A good rule of thumb is to stay as natural as possible.

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